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Cal 500mg Tablet 1 Strip
Active Ingredient: Calcium Carbonate 500 mg
Dosage Form: Oral Tablet
Therapeutic Class: Antacid / Mineral Supplement
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✅ Description:
Calcium carbonate acts as a fast-acting antacid, neutralizing excess gastric acid in the stomach. While it provides quick symptomatic relief, prolonged use at high doses may stimulate rebound acid secretion and increase the risk of hypercalcemia, metabolic alkalosis, and milk-alkali syndrome.
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✔️ Indications
- Relief of heartburn, indigestion, and gastric upset
- Management of calcium deficiency and hypocalcaemia
- Adjunct in the treatment of hyperphosphatemia, especially in chronic kidney disease
- Used as a calcium supplement in dietary insufficiency
✔️ Dosage & Administration
Adults:
- Hyperacidity: 1–2 tablets as needed, up to a maximum of 16 tablets per day. Tablets may be sucked or chewed.
Hyperphosphatemia (chronic renal failure):
- Initial: 2.5 g/day
- Maximum: 17 g/day, administered in divided doses
✔️ Renal Dose Adjustment
In renal impairment (CrCl <25 ml/min):
Dosage may need adjustment based on serum calcium levels. Regular monitoring is advised.
✔️ Administration Guidance:
- Can be taken with or without food.
- For enhanced absorption, it is preferable to take it with meals.
- Avoid concurrent intake with high-fiber foods, as they may reduce calcium absorption.
✔️ Side Effects
- Gastrointestinal: Nausea, vomiting, anorexia, constipation, flatulence
- Metabolic: Hypercalcemia, metabolic alkalosis, milk-alkali syndrome
- Long-term use: Risk of acid rebound, gastric hypersecretion, and tissue calcification
✔️ Drug Interactions
May increase calcium levels when used with:
- Thiazide diuretics
- Vitamin D
- May decrease absorption of:
- Iron, zinc, tetracyclines, quinolones, atenolol, bisphosphonates (e.g., alendronate), sodium fluoride, calcium channel blockers
- May enhance the cardiotoxic effects of digitalis glycosides, increasing the risk of digoxin toxicity
- Reduced efficacy when co-administered with corticosteroids
✔️ Contraindications
- History of or current calcium-containing kidney stones
- Hypercalcemia
- Hypophosphatemia
- Suspected digoxin toxicity
✔️ Precautions
Use with caution in patients with:
- Renal impairment
- Hypoparathyroidism
- Conditions associated with elevated calcium levels
- Achlorhydria (calcium absorption may be reduced—prefer alternative salts and administer with meals)
- A history of nephrolithiasis (kidney stones)
- Pregnancy Category C
- Lactation: Considered safe; crosses the placenta and may be present in breast milk.
✔️ Storage
- Store in a cool, dry place.
- Protect from moisture and heat.
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The information contained herein should NOT be used as a substitute
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